Wound Healing Assay

/Wound Healing Assay
Wound Healing Assay 2017-11-09T12:59:30+00:00

Wound healing assays are used by a range of disciplines to study cell polarization, tissue matrix remodeling, estimate cell proliferation and migration rates of different culture conditions, study actin cytoskeletal structure regulation, as well as, a variety of other physiological processes. Wound healing is especially useful for studying the effect of cell-cell and cell-matrix interactions on cell migration. The assay is a simple and involves creating a scratch or “wound” in a confluent cell monolayer and then imaging the cells as the cell migrate to close the wound at regular intervals for several hours or days depending on the cell type and conditions. The images taken at regular intervals are then complied into a time-lapse movie. Wound confluence can then be graphed to quantitatively analyze the recovering surface of the wound.

Journal Articles

JuLI™ Br, Migration (Wound healing)

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The Effect of Pulsed Electric Field on Mesenchymal Stem Cell Direct Migration. (2016)

By K Jezierska-Woźniak, J Wojtkiewicz, Ł Grabarczyk, M Barczewska, A Habich, S Lipinski, W Maksymowicz
1st World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine and Food & Environmental Technologies

JuLI™ Br, Cell Migration

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Oxidized (non)-regenerated cellulose affects fundamental cellular processes of wound healing. (2016)

By M. U.Wagenhäuser, J. Mulorz, W. Ibing, F. Simon, J. M. Spin, H. Schelzig, and A. Oberhuber
Sci Rep

JuLI™ Br, Wound Healing

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Computational and experimental analysis of wound healing processe. (2016)

By Jinghu Liang, Antonio Bolea Albero, Jendrik Füller, Christel Müller-Goymann, and Markus Böl
PAMM (Proc Appl Math Mech)

JuLI™ Br, Wound Healing

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Sphingosine-1-phosphate receptor 1 expression in angiosarcoma: Possible role in metastasis and a potential therapeutic target. (2016)

By Daigo OKA, Risa KORESAWA, Hideyo FUJIWARA, Hirotake NISHIMURA, Isao IREI, Takashi AKIYAMA, Shuji HAMAZAKI, Wataru FUJIMOTO, Mikio MASUZAWA, Yoshito SADAHIRA
Kawasaki Medical Journal

JuLI™ FL, Migration (Wound healing)

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Stanniocalcin-2 (STC2): A potential lung cancer biomarker promotes lung cancer metastasis and progression. (2015)

By Sang-su Na, Mark Borris Aldonza, Hye-Jin Sung, Yong-In Kim, Yeon Sung Son, Sukki Cho, Je-Yoel Cho
Biochimica et Biophysica Acta (BBA) – Proteins and Proteomics

JuLI™ FL, Migration (Wound healing)

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In Vitro Effects of Phthalate Mixtures on Colorectal Adenocarcinoma Cell Lines. (2015)

By Begum Yurdakok Dikmen
Journal of Environmental Pathology, Toxicology and Oncology

JuLI™ Br, Migration (Wound healing)

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Pyk2 aggravates hypoxia-induced pulmonary hypertension by activating HIF-1α. (2015)

By Kuniyoshi Fukai, Akihiro Nakamura, Atsushi Hoshino, Naohiko Nakanishi, Yoshifumi Okawa, Makoto Ariyoshi, Satoshi Kaimoto, Motoki Uchihashi, Kazunori Ono, Shuhei Tateishi, Koji Ikeda, Takehiro Ogata, Tomomi Ueyama, Satoaki Matoba
American Journal of Physiology – Heart and Circulatory Physiology

JuLI™ Br, Migration (Wound healing)

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The effects of Akt1/Akt2 selective inhibition on tumorigenic properties of NSCLC cells. (2015)

By Ritesh Briah
Degree of Master

JuLI™ Br, Migration (Wound healing)

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Modulation of Intracellular Calcium Levels by Calcium Lactate Affects Colon Cancer Cell Motility through Calcium-Dependent Calpain. (2015)

By Pasupathi Sundaramoorthy
PLoS ONE

JuLI™, Migration (Wound healing)

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NME1L Negatively Regulates IGF1-Dependent Proliferation of Breast Cancer Cells. (2015)

By Dong-Joo You, Sunam Mander, Cho Rong Park, Okjae Koo, Cheolju Lee, Seong-Hyun Oh, Curie Ahn, Jae Young Seong, Jong-Ik Hwang
Journal of Cellular Biochemistry

JuLI™, Migration (Wound healing)

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Dynamin-related protein 1 controls the migration and neuronal differentiation of subventricular zone-derived neural progenitor cells. (2015)

By Hyun Jung Kim, Mohammed R. Shaker, Bongki Cho, Hyo Min Cho, Hyun Kim, Joo Yeon Kim, and Woong Sun
Scientific Reports

JuLI™, Migration (Wound healing)

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Poisson-event-based analysis of cell proliferation. (2015)

By Huw D. Summers, John W. Wills, M. Rowan Brown, and Paul Rees
Cytometry A

JuLI™ FL, Migration (Wound healing)

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Caffeic Acid Reduces the Viability and Migration Rate of Oral Carcinoma Cells (SCC-25) Exposed to Low Concentrations of Ethanol. (2014)

By Arkadiusz Dziedzic
Int. J. Mol. Sci

JuLI™, Migration (Wound healing)

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Mechanisms of buffer therapy resistance. (2014)

By Kate M. Bailey
Neoplasia

JuLI™, Migration (Wound healing)

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A polydimethylsiloxane–polycarbonate hybrid microfluidic device capable of enerating perpendicular chemical and oxygen gradients for cell culture studies. (2014)

By Chia-Wen Chang, Yung-Ju Cheng, Melissa Tu, Ying-Hua Chen, Chien-Chung Peng, Wei-Hao Liao and Yi-Chung Tung
Lab on a Chip

JuLI™, Migration (Wound healing)

Journal Link

Manipulating the Tumor Microenvironment for Therapeutic Benefit. (2014)

By Kate M. Bailey
Degree of Doctor

JuLI™, Migration (Wound healing)

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Water fluxes through aquaporin-9 prime epithelial cells for rapid wound healing. (2013)

By Karlsson T, Lagerholm BC, Vikström E, Loitto VM, Magnusson KE
Biochem Biophys Res Commun